Dimethyltryptamine (DMT)
N,N-Dimethyltryptamine has a long history of
use and is found in a variety of plants and
seeds. It can also be produced synthetically. It
combined with another drug that inhibits its
metabolism.

Generally it is sniffed, smoked, or injected. The
effective hallucinogenic dose in humans is about
50 to 100 mg and lasts for about 45 to 60
minutes.

Because the effects last only about an hour; the
experience has been referred to as a
"businessman's trip."

A number of other hallucinogens have very
similar structures and properties to those of
DMT. Diethyltryptamine (DET)
N,N-Diethyltryptamine, for example, is an
analogue of DMT and produces the same
pharmacological effects but is somewhat less
potent than DMT. Alpha-ethyltryptamine (AET) is
another tryptamine hallucinogen added to the
list of Schedule I hallucinogens in 1994.
Bufotenine (5-hydroxy-N,N-dimethyltryptamine)
is a Schedule I substance found in certain
mushrooms, seeds, and skin glands of Bufo
toads.

In general, most bufotenine preparations from
natural sources are extremely toxic.
N,N-Diisopropyl-5-methoxytryptamine (referred
to as Foxy-Methoxy) is an orally active
tryptamine recently encountered in the United
States.
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